In the production process, machines, peoples, materials, methods and environment lead to fluctuations in the results accuracy. Normal fluctuations have less impact on product quality and it is technically inevitable but abnormal fluctuations has more impact and lead to defects. SPC – Statistical process control is a process control methodology using statistical methods and was invented for the first time using control charts at 1924 at Bell Laboratories in USA. SPC is widely applied to Quality Management. Since there SPC was developed and continue to produce many kinds of new methods in practice. There is many statistical software on the market which provide for different kinds of solutions - MINITAB, Statgraphics, JMP/SAS, SPSS, Statistics and Q-DAS.